Regularly engaged at the world’s leading opera houses, she has recently performed at the Wiener Staatsoper, Metropolitan Opera, the Salzburger Festspiele, the Royal Opera House, London and Teatro alla Scala.
Asmik works with many of the world's leading conductors including Franz Welser-Möst, Yves Abel, Vladimir Jurowski, Mikhail Tatarnikov, Alan Gilbert. She also frequently collaborates with top stage directors including Dmitri Tcherniakov, Romeo Castellucci, and Claus Guth.
She was a founding member of Vilnius City Opera, has twice been awarded the Golden Stage Cross (the highest award for singers in Lithuania), was named Best Female Lead in 2019 at the Austrian Music Theater Awards, and was named Female Opera Singer of the Year in 2022 by the Ópera XXI Association. She won Opus Klassik's 2023 Female Singer of the Year in recognition of her acclaimed debut album Dissonance with pianist Lukas Geniušas. In 2024, she received the Grand Jury Prize at the Austrian Music Theatre Awards, as well as the Theaterpreis DER FAUST Award for her performance as Salome at the Staatsoper Hamburg.
She made her debut at the Gran Teatre del Liceu in the 2017/18 season with Demon and has returned with Rusalka and Asmik Grigorian and Matthias Goerne in concert (2024/25).